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Studies in the Pharmacology of Local Anesthetics

IV. The Examination of the Urine and Blood of Dogs Injected Subcutaneously With Neothesin*

Indianapolis, Ind.

Abstract

THE STUDY OF PLANT and animal life has revealed just as perplexing and important problems in the katabolic phase of metabolism as in the anabolic. To be sure, the degree of importance of the one or the other phase differs with the substances being studied. Thus, the food chemist would be primarily interested in the assimilation phenomena, while the pharmacologist, in the study of a compound having therapeutic applications, would consider more important the dissimilation and mode of elimination. The pharmacologic picture, therefore, of a medicinal, and more specifically in the case to be discussed, of a new local anesthetic would be properly incomplete unless some knowledge were gained as to the mode and rates of excretion.

Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999