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The Rectal Instillation of Certain Barbiturates in Ether and Oil With Quinin for Obstetrical Analgesia.*

Anesthetist. Cleveland. Ohio.

Abstract

SINCE THE INTRODUCTION of barbital by Fischer and Von Mering,¹ in 1904, the extensive use of barbital as an hypnotic agent has not only stimulated the development of other barbituric acid compounds but from an anesthetist's viewpoint they have opened a fertile field for anesthesia premedication. The pharmacological study of the various barbiturates have been investigated and reported by quite a few authorities, but the work of Nielsen, Higgins and Spruth² on their comparative study of hypnotics of the barbituric acid series, established a method for obtaining dependable results, which was very necessary in the face of so many claims for the different compounds.

Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999