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Anesth Analg 2005;100:192-195
© 2005 International Anesthesia Research Society
doi: 10.1213/01.ANE.0000139345.85653.AB

CRITICAL CARE AND TRAUMA

Blindness in the Intensive Care Unit: Possible Role for Vasopressors?

Lorri A. Lee, MD*, Avery B. Nathens, MD{dagger},{ddagger}, Bryan S. Sires, MD, PhD§, Megan K. McMurray, PharmD||, and Arthur M. Lam, MD, FRCPC*,¶

Departments of *Anesthesiology, {dagger}Surgery, {ddagger}Critical Care, §Ophthalmology, ||Pharmacy, and ¶Neurological Surgery, University of Washington, Seattle, Washington

Address correspondence and reprint requests to Lorri A. Lee, MD, Harborview Medical Center, Department of Anesthesiology, Box 359724, 325 Ninth Ave., Seattle, WA 98104. Address e-mail to lorlee{at}u.washington.edu

Blindness caused by ischemic optic neuropathy in the hospital setting occurs perioperatively and in critically ill patients, but its etiology remains ill defined. We describe four critically ill patients who developed blindness within 1 mo of one another. Three cases occurred outside of the operative arena. Potential risk factors for the development of ischemic optic neuropathy, such as use of vasopressors, venous congestion, and hypotension, are described.

IMPLICATIONS: Four cases of blindness in critically ill patients are described, three of which occurred outside the operative arena. Venous congestion and hypotension are among the potential risk factors for the development of ischemic optic neuropathy. The role of vasopressors remains speculative but should be considered during treatment of critically ill patients.




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S. M. Jakob
Blindness in the Intensive Care Unit
Anesth. Analg., January 1, 2005; 100(1): 189 - 191.
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Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2005 by the International Anesthesia Research Society.