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REGIONAL ANESTHESIA

The Effects of Stellate Ganglion Block on Visual Evoked Potential and Blood Flow of the Ophthalmic and Internal Carotid Arteries in Patients with Ischemic Optic Neuropathy

Feng Liu, PhD^*, Guozhong Xu, MB^*, Zheli Liu, PhD, Yan Zhao, MM, Xiaojun Lv, MM, and Junke Wang, MM^*

Departments of *Anesthesiology and Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, China; and Departments of Stomach Surgery and Internal Medicine, LiaoNing Cancer Hospital, Shenyang, China

Address correspondence and reprint requests to Feng Liu, PhD, Department of Anesthesiology, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China. Address e-mail to liufeng024{at}yahoo.com.cn.

Ischemic optic neuropathy (ION) is a common disease that can cause a loss of visual acuity in the elderly. We treated ION patients with stellate ganglion block (SGB) and investigated its effects on picture visual evoked potential (P-VEP) and blood flow in the ophthalmic artery (OA) and internal carotid artery (ICA). Twelve ischemic eyes in 12 patients diagnosed by the same ophthalmologist were investigated in this study. All patients were treated with daily SGB on the affected side with 2–3 mL of 2% lidocaine for a treatment period of 10–15 days. In ION eyes before SGB, compared with healthy eyes, the latency of P-VEP P₁₀₀ was delayed (123 ± 14 ms versus 98 ± 3 ms; P < 0.05), and the amplitude was reduced (4.24 ± 1.76 µV versus 10.26 ± 4.09 µV; P < 0.05). After SGB, the latency and amplitude returned to normal (103 ± 6 ms versus 98 ± 3 ms; 10.43 ± 4.88 µV versus 10.26 ± 4.09 µV; P > 0.05). Before treatment, the blood flow velocities of the OA and the ICA on the ischemic side were slow and the resistance indexes were high, but SGB reduced these changes. SGB did not affect the OA and the ICA on the healthy side. We conclude that SGB improves P-VEP and OA and ICA blood flow in ION eyes. Further studies are needed to confirm that this is an effective method for the treatment of ION.