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Anesth Analg 2005;100:1303-1305
© 2005 International Anesthesia Research Society
doi: 10.1213/01.ANE.0000149602.85276.71


PEDIATRIC ANESTHESIA

Accuracy in the Alteration of Acetaminophen Suppositories

Tae W. Kim, MD, Cheryl L. Rognerud, MT(ASCP), MS, and Ching-Nan Ou, PhD

Department of Anesthesiology, Baylor College of Medicine, Texas Children’s Hospital

Address correspondence and reprint requests to Tae W. Kim, MD, 6621 Fannin St Ste B310, MC 2–1495, Houston, TX 77030–2399. Address e-mail to twkim{at}bcm.tmc.edu.

Many pediatric anesthesiologists divide acetaminophen suppositories to achieve an approximate dose. In this three-part study we first surveyed pediatric anesthesiologists regarding their attitudes and frequency of this clinical practice. Second, acetaminophen suppositories were divided for analysis of acetaminophen content. Finally, the accuracy of pediatric anesthesiologists in dividing suppositories was assessed. The survey indicated 50% of anesthesiologists believed acetaminophen was nonuniform and 62% believed the alteration of suppositories was inaccurate. The laboratory investigation revealed uniform distribution of acetaminophen but poor accuracy in achieving the target dose. The findings suggest using only intact suppositories for improved accuracy.




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Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2005 by the International Anesthesia Research Society.