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Anesth Analg 2005;101:726-727
© 2005 International Anesthesia Research Society
doi: 10.1213/01.ANE.0000159376.47974.71

ANESTHETIC PHARMACOLOGY

Physostigmine for the Acute Treatment of Restless Legs Syndrome

Calvert C. Alpert, MD, D. Patrick Tobin, CRNA, and Stephen F. Dierdorf, MD

Department of Anesthesia and Perioperative Medicine, Medical University of South Carolina, Charleston, South Carolina

Address correspondence and reprint requests to Stephen F. Dierdorf, MD, Department of Anesthesia and Perioperative Medicine, Medical University of South Carolina, 165 Ashley Avenue, Suite 525, PO Box 250912, Charleston, South Carolina 29425. Address e-mail to dierdorf{at}musc.edu.

We present a case report of an acute episode of restless legs syndrome that interfered with the performance of a diagnostic imaging procedure of the cervical spine. The patient had a 19-yr history of restless leg syndrome with periodic limb movements during sleep. Treatment with additional sedation and opioids did not alleviate the leg movements. IV administration of 1 mg of physostigmine eradicated all extraneous leg motion.






Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2005 by the International Anesthesia Research Society.