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Anesth Analg 2005;101:916-919
© 2005 International Anesthesia Research Society
doi: 10.1213/01.ANE.0000175208.76574.54


GENERAL ARTICLES

Transient Global Amnesia After General Anesthesia

Ryan J. Bortolon, MD, Margaret R. Weglinski, MD, and Juraj Sprung, MD, PhD

Department of Anesthesiology, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota

Address correspondence and reprint requests to Juraj Sprung, MD, PhD, Department of Anesthesiology, Mayo Clinic Mayo Clinic College of Medicine, Mary Brigh 2–752 200 First Street SW, Rochester, MN 55905. Address electronic mail to sprung.juraj{at}mayo.edu.

Transient global amnesia (TGA) is an amnestic syndrome, clinically dramatic but benign in nature. The hallmark of TGA is brief inability to form new memories and recall past memories despite otherwise normal neurological function. In a significant number of patients with TGA a stressful precipitating factor can be identified. We report two cases of TGA after uneventful general anesthesia. Anesthesia per se does not appear to be a direct trigger of TGA, as our first patient had a second anesthetic the next day without recurrence of TGA. Because the presentation of TGA can be dramatic and may mimic an acute cerebral ischemic event, a thorough neurologic evaluation should be pursued.







Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2005 by the International Anesthesia Research Society.