JOURNAL HOME CME HOME THIS MONTH PAST ISSUES ETOC COLLECTIONS
AUTHORS REVIEWERS EDITORIAL BOARD FEEDBACK RSS HELP
A&A International Anesthesia Research Society
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a colleague
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (18)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Noto, Y.
Right arrow Articles by Hirota, K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Noto, Y.
Right arrow Articles by Hirota, K.
Related Collections
Right arrow Economics and Health Care Research
Right arrow Preoperative Evaluation

Anesth Analg 2005;101:1873-1876
© 2005 International Anesthesia Research Society
doi: 10.1213/01.ANE.0000184196.60838.8D

GENERAL ARTICLES

The Relationship Between Salivary Biomarkers and State-Trait Anxiety Inventory Score Under Mental Arithmetic Stress: A Pilot Study.

Yuka Noto*, Tetsumi Sato{dagger}, Mihoko Kudo{dagger}, Kiyoshi Kurata{ddagger}, and Kazuyoshi Hirota{dagger}

Department of *Nursing, {dagger}Anesthesiology, and {ddagger}First Department of Physiology, Hirosaki University School of Health Sciences, Japan

Address correspondence and reprint requests to Kazuyoshi Hirota, MD, FRCA, Department of Anesthesiology, Hirosaki University School of Medicine, Hirosaki 036–8563, Japan. Address e-mail to masuika{at}cc.hirosaki-u.ac.jp.

Measurement of stress hormones is a common objective method for assessment of mental stress. However, the stress of blood sampling alone may also increase stress hormone levels. In the present study, we sampled salivary biomarkers from healthy volunteers under noninvasive conditions and determined their efficacy to assess mental stress. Specifically, we examined the relationship between State Anxiety Inventory score (STAI-s) in subjects exposed to arithmetic stress and salivary chromogranin-A, {alpha}-amylase, or cortisol. The STAI-s was significantly correlated to salivary {alpha}-amylase (r = 0.589; P < 0.01) but not to salivary chromogranin-A or cortisol. Therefore, salivary {alpha}-amylase is a useful indicator of psychosocial stress.




This article has been cited by other articles:


Home page
 aacredbookHome page
S. D Conzen
Environmental Stress and the Neuroendocrine Response: Is There a Cancer Connection?
Am. Assoc. Cancer Res. Educ. Book, April 12, 2008; 2008(1): 255 - 262.
[Abstract] [Full Text] [PDF]

Home page
 Occup. Environ. Med.Home page
D. Soo-Quee Koh and G. Choon-Huat Koh
The use of salivary biomarkers in occupational and environmental medicine
Occup. Environ. Med., March 1, 2007; 64(3): 202 - 210.
[Full Text] [PDF]


Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins and Stanford University Libraries' HighWire Press®. Copyright 2005 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2005 by the International Anesthesia Research Society.