Anesth Analg 2006;102:372-375
© 2006 International Anesthesia Research Society
doi: 10.1213/01.ane.0000189596.70694.36
CARDIOVASCULAR ANESTHESIA
Malignant Hyperthermia Following Systemic Rewarming After Hypothermic Cardiopulmonary Bypass
Adam D. Lichtman, MD*, and
Charles Oribabor, MD
Department of *Anesthesiology, Weill-Cornell Medical Center, New York, New York; and Cardiothoracic Intensive Care Unit, New York Methodist Hospital, Brooklyn, New York
Address correspondence and reprint requests to Adam Lichtman, MD, 356 Clinton Street #2, Brooklyn NY 11231. Address e-mail to divemd{at}att.net.
Malignant hyperthermia (MH) is a rare hypermetabolic disorder of skeletal muscle that can be fatal if not recognized and treated aggressively. We describe a patient with a suspected family history of MH who developed hyperpyrexia, acidosis, and hypermetabolism after cardiac surgery despite a nontriggering anesthetic. No drugs were identified as being causative and we theorize that systemic rewarming was the inciting cause of MH in this MH-susceptible individual via a mechanism similar to heat stroke.
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