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Anesth Analg 2006;102:372-375
© 2006 International Anesthesia Research Society
doi: 10.1213/01.ane.0000189596.70694.36

CARDIOVASCULAR ANESTHESIA

Malignant Hyperthermia Following Systemic Rewarming After Hypothermic Cardiopulmonary Bypass

Adam D. Lichtman, MD*, and Charles Oribabor, MD{dagger}

Department of *Anesthesiology, Weill-Cornell Medical Center, New York, New York; and {dagger}Cardiothoracic Intensive Care Unit, New York Methodist Hospital, Brooklyn, New York

Address correspondence and reprint requests to Adam Lichtman, MD, 356 Clinton Street #2, Brooklyn NY 11231. Address e-mail to divemd{at}att.net.

Malignant hyperthermia (MH) is a rare hypermetabolic disorder of skeletal muscle that can be fatal if not recognized and treated aggressively. We describe a patient with a suspected family history of MH who developed hyperpyrexia, acidosis, and hypermetabolism after cardiac surgery despite a nontriggering anesthetic. No drugs were identified as being causative and we theorize that systemic rewarming was the inciting cause of MH in this MH-susceptible individual via a mechanism similar to heat stroke.




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Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2006 by the International Anesthesia Research Society.