Anesth Analg 2006;103:309-311
© 2006 International Anesthesia Research Society
doi: 10.1213/01.ane.0000226087.11062.cd
CARDIOVASCULAR ANESTHESIA
Perioperative Management of a Heterozygous Carrier of Glanzmanns Thrombasthenia Submitted to Coronary Artery Bypass Grafting With Cardiopulmonary Bypass
Valter Casati, MD*,
Armando DAngelo, MD ,
Luciano Barbato, MD ,
Edoardo Rossi, MD ,
Maria Antonietta Grasso, MD*,
Salvatore Spagnolo, MD , and
Ezio Panzeri, MD
From the *Division of Cardiovascular Anesthesia and Intensive Care, Policlinico di Monza, Monza, Italy; Coagulation Service and Thrombosis Research Unit, Ospedale San Raffaele, Milano, Italy; Division of Cardiac Surgery, Policlinico di Monza, Monza, Italy; Division of Hematology, Ospedale Sacco, Milano, Italy.
Address correspondence and reprint requests to Valter Casati, MD, Division of Cardiovascular Anesthesia and Intensive Care, Policlinico di Monza, via Amati 111, Monza (20052), Italy. Address e-mail to valter.casati{at}policlinicodimonza.it.
Glanzmanns thrombasthenia is a congenital hemorrhagic disorder transmitted as an autosomal recessive trait and characterized by altered production and/or assembly of the platelet membrane glycoprotein IIb/IIIa receptor. We describe the perioperative management of a heterozygous carrier of Glanzmanns thrombasthenia submitted to cardiac surgery with cardiopulmonary bypass and the case was complicated by early excessive postoperative bleeding.
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