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Anesth Analg 2006;103:1109-1112
© 2006 International Anesthesia Research Society
doi: 10.1213/01.ane.0000239330.45658.76

CARDIOVASCULAR ANESTHESIA

Nonlinear Heart Rate Variability Analysis May Predict Atrial Fibrillation After Coronary Artery Bypass Grafting

Dmitri Chamchad, MD*, George Djaiani, MD{dagger}, Hyun Ju Jung, MD{dagger}, Lev Nakhamchik, MSc{dagger}, Jo Carroll, RN{dagger}, and Jay C. Horrow, MD, MS{ddagger}

From the *Department of Anesthesia, Lankenau Hospital, Wynnewood, Pennsylvania; {dagger}Department of Anesthesia, Toronto General Hospital, Toronto, Ontario, Canada; and {ddagger}Department of Anesthesia, Drexel University College of Medicine, Philadelphia, Pennsylvania.

Address correspondence and reprint requests to Jay Horrow, MD, MS, Mail Stop 310, Broad and Vine, Philadelphia, PA 19102-1192. Address e-mail to jhorrow{at}drexelmed.edu.

BACKGROUND: Heart rate variability might predict arrhythmias after coronary artery bypass grafting.

METHODS: Off-line processing of 10-min electrocardiogram recordings of consecutive patients provided R–R intervals for time domain, frequency domain, Poincaré, and point correlation analyses and subsequent association with postoperative atrial fibrillation by stepwise multivariate logistic regression.

RESULTS: Of 88 patients who met entry criteria, 13 developed atrial fibrillation. Peak point correlation dimension (odds ratio 3.985/unit, P = 0.0096) and age (odds ratio 1.144/yr, P = 0.0019) were independently associated with atrial fibrillation (c-statistic = 0.839).

CONCLUSIONS: Further study should confirm the ability of peak point correlation dimension to predict atrial fibrillation after coronary artery surgery with cardiopulmonary bypass.






Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2006 by the International Anesthesia Research Society.