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From the Departments of *Anesthesiology, Critical Care and Pain Management, and
Urology, Meir Medical Center, Kfar Saba, The Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Address correspondence and reprint requests to Brian Fredman, MB BCh, Department of Anesthesiology and Intensive Care, Meir Medical Center, Kfar Saba 44281, Israel. Address e-mail to fredman.brian{at}clalit.org.il.
One hundred elderly men (
65 yr) undergoing transurethral procedures (<45 min) received bupivacaine 7.5 mg, or bupivacaine 5 mg + fentanyl 20 µg, or bupivacaine 4 mg + fentanyl 20 µg, or bupivacaine 3 mg + fentanyl 20 µg, intrathecally. Intraoperative "rescue" fentanyl requirements were higher (P < 0.03) in group bupivacaine 3 mg + fentanyl. Times (min) to ambulation eligibility were decreased in a dose-dependant manner (157 ± 50 vs 147 ± 37 vs 128 ± 40 vs 116 ± 29, respectively). Of the techniques studied, intrathecal bupivacaine 4 mg + fentanyl 20 µg provided adequate analgesia and was associated with hemodynamic stability and a favorable recovery profile.
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E. Zohar and B. Fredman Minimum Effective Dose of Bupivacaine Required for Transurethral Procedures Remains Uncertain Anesth. Analg., October 1, 2007; 105(4): 1170 - 1170. [Full Text] [PDF] |
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