Anesth Analg 2007;104:585-586
© 2007 International Anesthesia Research Society
doi: 10.1213/01.ane.0000253231.76654.45
ANESTHETIC PHARMACOLOGY
Emergency Use of Sugammadex After Failure of Standard Reversal Drugs
Adam Lenz, MD,
Gary Hill, MD, and
Paul F. White, MD, PhD
From the Department of Anesthesiology and Pain Management; University of Texas Southwestern Medical Center, Dallas, Texas.
Address correspondence and reprint requests to Paul F. White, MD, PhD, Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9068. Address e-mail to paul.white{at}utsouthwestern.edu.
Administration of sugammadex, 350 mg IV (4 mg/kg), in the postanesthesia care unit immediately (<60 s) relieved acute respiratory distress due to residual neuromuscular blockade in a 42-yr-old patient with chronic renal failure who had received vecuronium, 10 mg IV, for tracheal intubation, after inadequate reversal of neuromuscular blockade in the operating room with neostigmine, 5 mg IV, and glycopyrrolate, 1 mg IV.
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