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Address correspondence and reprint requests to Jie Zhang, Department of Anesthesiology, The First Affiliated Hospital of ZhengZhou University, No. 1 East-JianShe Road, ZhengZhou 450052, China. Address e-mail to joannyzh{at}hotmail.com.
Abstract
BACKGROUND: We evaluated sevoflurane requirements during combined general-epidural anesthesia with different concentration of ropivacaine.
METHODS: Fifty-six patients were randomly divided into three groups to epidurally receive saline, 0.2% ropivacaine or 1% ropivacaine. Sevoflurane concentration was adjusted to maintain certain anesthesia depth. BIS values and end-tidal sevoflurane concentrations were recorded at time points of pre-intubation and 5 min, 10 min, 15 min, 20 min, 25 min, 30 min after intubation.
RESULTS: End-tidal sevoflurane was significantly lower in the group receiving higher concentration of sevoflurane.
CONCLUSIONS: Epidural anesthesia can decrease sevoflurane requirements to a larger extent when a higher concentration of ropivacaine was applied.
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