Anesth Analg 2007;104:984-986
© 2007 International Anesthesia Research Society
doi: 10.1213/01.ane.0000258765.16164.27
ANALGESIA
The Effect of Epidural Anesthesia with Different Concentrations of Ropivacaine on Sevoflurane Requirements
Jie Zhang, BS,
Wei Zhang, MS, and
Bin Li, MS
Address correspondence and reprint requests to Jie Zhang, Department of Anesthesiology, The First Affiliated Hospital of ZhengZhou University, No. 1 East-JianShe Road, ZhengZhou 450052, China. Address e-mail to joannyzh{at}hotmail.com.
Abstract
BACKGROUND: We evaluated sevoflurane requirements during combined general-epidural anesthesia with different concentration of ropivacaine.
METHODS: Fifty-six patients were randomly divided into three groups to epidurally receive saline, 0.2% ropivacaine or 1% ropivacaine. Sevoflurane concentration was adjusted to maintain certain anesthesia depth. BIS values and end-tidal sevoflurane concentrations were recorded at time points of pre-intubation and 5 min, 10 min, 15 min, 20 min, 25 min, 30 min after intubation.
RESULTS: End-tidal sevoflurane was significantly lower in the group receiving higher concentration of sevoflurane.
CONCLUSIONS: Epidural anesthesia can decrease sevoflurane requirements to a larger extent when a higher concentration of ropivacaine was applied.
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