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TECHNOLOGY, COMPUTING, AND SIMULATION

The Effect of Intravenous Indigo Carmine on Near-Infrared Cerebral Oximetry

David L. McDonagh, MD^*, Matthew R. McDaniel, BS, and Terri G. Monk, MD^*

From the *Department of Anesthesiology, Duke University Medical Center and Durham Veterans Affairs Medical Center, Durham; and University of North Carolina School of Medicine, Chapel Hill, North Carolina.

Address correspondence and reprint requests to David L. McDonagh, MD, DUMC, Box 3094, Durham, NC 27710. Address e-mail to david.mcdonagh{at}duke.edu.

The effects of IV-administered dyes on pulse oximetry have been well described. However, the effects on near-infrared cerebral oximetry have not been well documented. We report a series of four patients undergoing radical prostatectomy who were monitored with cerebral oximetry during surgery. After the administration of indigo carmine, intraoperative desaturations were observed for an extended period. Because clinical use of near-infrared cerebral oximetry is increasing, anesthesiologists should be aware of this issue.

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