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REVIEW

Automated Regulation of Inspired Oxygen in Preterm Infants: Oxygenation Stability and Clinician Workload

From the Division of Neonatology, Department of Pediatrics, University of Miami Miller School of Medicine, Miami, Florida.

Address correspondence and reprints requests to Nelson Claure, Division of Neonatology, Department of Pediatrics, University of Miami School of Medicine, P.O. Box 016960 R-131, Miami, FL 33101. Address e-mail to NClaure{at}miami.edu.

Abstract

Premature infants are at an increased risk of ophthalmic, neurologic, and respiratory sequelae related to inadequate maintenance of oxygenation and exposure to increased levels of inspired oxygen. Management of inspired oxygen is complicated in this population by an increased variability in oxygenation. Automated regulation of the fraction of inspired oxygen is a technology that has a potential of improving such outcomes as well as impacting personnel workload. This is a review of current experimental evidence on the effectiveness of automated regulation of inspired oxygen and its effects on oxygenation variability and personnel workload during the care of premature infants.