Anesth Analg 2008; 107:1260-1262
© 2008 International Anesthesia Research Society
doi: 10.1213/ane.0b013e31817d8637
PATIENT SAFETY
Bronchospasm After Intravenous Lidocaine
Bobby R. Burches, Jr, BS, and
David O. Warner, MD
From the Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota.
Address correspondence to David O. Warner, MD, Mayo Clinic, 200 1st St. SW, Rochester, MN 55905. Address e-mail to warner.david{at}mayo.edu.
Abstract
IV lidocaine (1.5 mg/kg) administered to facilitate endotracheal intubation was associated with transient bronchospasm in a 17-month-old-female with mild intermittent asthma. Immediately after lidocaine administration, the patient developed diffuse bilateral expiratory wheezes and dramatic increases in peak inspiratory pressure. Over approximately 5 min the episode resolved and an uneventful anesthetic course followed. This is consistent with recent clinical studies suggesting that IV lidocaine may cause airway narrowing in asthmatics. Practitioners should be aware of this potential complication.
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