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CARDIOVASCULAR ANESTHESIOLOGY

Perioperative Management of a Child with von Willebrand Disease Undergoing Surgical Repair of Craniosynostosis: Looking at Unusual Targets

Isabelle Maquoi, MD^*, Vincent Bonhomme, MD, PhD^*, Jacques Daniel Born, MD, PhD, Marie-Françoise Dresse, MD, PhD, Elisabeth Ronge-Collard, MD^||, Jean-Marc Minon, MD, PhD^||, and Pol Hans, MD, PhD^*

From the *University Department of Anesthesia and ICM, Department of Neurosurgery, University Department of Pediatrics, Liege Hemophilia Treatment Center, and ||Department of Laboratory Medicine, Hemostasis and Thrombosis Unit, CHR Citadelle, Liege, Belgium.

Address correspondence to Pol Hans, MD, PhD, University Department of Anesthesia and ICM, Bd du 12eme de Ligne, 1, 4000 Liege, Belgium. Address e-mail to pol.hans{at}chu.ulg.ac.be.

Abstract

We report the successful management of a craniosynostosis repair in a child with severe Type I von Willebrand disease diagnosed during the preoperative assessment and treated by coagulation factor VIII and ristocetin cofactor. Collaboration among the anesthesiologist, the neurosurgeon, the clinical pathologist, and the pediatric hematologist is important for successful management.