This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a colleague Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Articles by RACKOW, H. Articles by SALANITRE, E. Search for Related Content PubMed PubMed Citation Articles by RACKOW, H. Articles by SALANITRE, E.

The Pulmonary Absorption-Excretion Volume Effect

HERBERT RACKOW, MD^*, and ERNEST SALANITRE, MD

*Professor of Anesthesiology, Department of Anesthesiology, College of Physicians and Surgeons, Columbia University and the Anesthesiology Service of Presbyterian Hospital, New York, New York 10032. Professor of Clinical Anesthesiology, College of Physicians and Surgeons, Columbia University and the Anesthesiology Service of Presbyterian Hospital, New York, New York 10032.

Abstract

An in-vitro experiment demonstrated the concentration effect of N₂O (3% versus 75%) during elimination and during uptake. Other pulmonary absorption-excretion phenomena also occur simultaneously, as paired events during uptake and then during elimination diffusion hyperoxia and diffusion anoxia; alveolar concentration of CO₂, and alveolar dilution of CO₂. These clinical phenomena, as well as the second gas effect, are all related, and the pulmonary absorption-excretion volume is found to depend in part on the type of ventilation: volume controlled, pressure controlled, or spontaneous respiration.