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Anesth Analg 1976; 55:388-391
© 1976 International Anesthesia Research Society
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Circulatory Responses and Halothane Concentrations During Gastric or Gallbladder Traction With and Without Neuromuscular Blockade

ROBERT K. STOELTING, MD*, CHRISTINE PETERSON, RN{dagger}, and JAMES A. MADURA, MD{ddagger}

*Associate Professor of Anesthesia/Pharmacology. Indiana University School of Medicine. Indianapolis. Indiana 46'202 {dagger}Anesthesia Research Nurse. Indiana University School of Medicine. Indianapolis. Indiana 46'202 {ddagger}Assistant Professor of Surgery. Indiana University School of Medicine. Indianapolis. Indiana 46202

Abstract

Systolic and diastolic blood pressures and heart rates did not change significantly and ventricular dysrhythmias did not occur during gastric or gallbladder traction in patients anesthetized with N2O-halothane, with or without d-tubocurarine or pancuronium neuromuscular blockade.

Systolic and diastolic blood pressures and heart rates just before abdominal riscera traction were less (p<0.05) in patients paralyzed with d-tubocurarine than with pancuronium despite similar arterial halothane concentrations. In contrast, these measurements in patients without neuromuscular blockade were similar to those during pancuronium paralysis despite significantly greater arterial halothane concentrations in the unparalyzed patients.

The authors conclude that circulatory responses during gastric or gallbladder traction are clinically insignificant during N20-halothane administration, with or without d-tubocurarine or pancuronium neuromuscular blockade. Intra-operative blood pressures and heart rates were influenced by the neuromuscular blocker chosen. Neuromuscular blockade permitted anesthetic maintenance with lower arterial halothane concentrations than when paralysis was not present.






Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins and Stanford University Libraries' HighWire Press®. Copyright 1976 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1976 by the International Anesthesia Research Society.