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Anesth Analg 1981; 60:715-719
© 1981 International Anesthesia Research Society
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Hemodynamic Effects of Butorphanol-Oxygen Anesthesia in Dogs

James Sederberg, MD*, Theodore H. Stanley, MD{dagger}, Prasad Reddy, MD{ddagger}, Wen-Shin Liu, MD§, David Port, BS||, and Stephen Gillmor, BS||

*Fellow. {dagger}Professor. {ddagger}Assistant Professor. §Instructor. ||Research Technician. Received from the Department of Anesthesiology, The University of Utah College of Medicine, So. Medical Drive, Salt Lake City, Utah 84132.

Abstract

The cardiovascular effects of two intravenous rates of butorphanol infusion (0.1 and 0.2 mg/kg/min) were measured in 32 dogs breathing oxygen and nitrous oxide in oxygen. Sixteen dogs were premedicated with atropine and the other 16 were unpremeditated. Of the dogs receiving the higher dose infusion rate, 25% moved with a tail-clamp stimulus whereas 75% moved with the lower doses. Butorphanol produced significant but similar cardiovascular depression with the two rates of infusion irrespective of the presence or absence of atropine medication. Addition of nitrous oxide resulted in further cardiac depression in all groups studied. The data suggest that butorphanol is not an attractive alternative to morphine or fentanyl as a narcotic anesthetic.

Key Words: ANALGESICS: butorphanol.






Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1981 by the International Anesthesia Research Society.