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Anesth Analg 1983; 62:975-981
© 1983 International Anesthesia Research Society
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Chronic Obstructive Pulmonary Disease and Respiratory Complications

Martin I. Gold, MD, Stephen J. Schwam, MD, and Myron Goldberg, PhD

Departments of Anesthesiology and Neurological Surgery, University of Miami School of Medicine, and the Veterans Administration Medical Center, Miami, Florida.

Abstract

Patients with chronic obstructive pulmonary disease (COPD) (N = 148) underwent general anesthesia with halothane (H) or isoflurane (I) each administered randomly to 74 patients. One hundred and ten pre-, intra-, and postoperative variables were analyzed, including outcome variables, which included intra- and postoperative respiratory complications. Univariate computer analyses demonstrated no differences between H and I groups with respect to all variables, the exception being tachycardia, which occurred significantly more frequently in patients given I. Log-linear analyses revealed that no interactions existed between H or I groups, the non-outcome variables, and the complications. We conclude that patients with COPD respond similarly to H and I and that these anesthetics are associated with similar incidences of respiratory complications.

Key Words: LUNG: obstructive pulmonary disease • COMPLICATIONS: respiratory • ANESTHETICS, Volatile: halothane; isoflurane






Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1983 by the International Anesthesia Research Society.