JOURNAL HOME CME HOME THIS MONTH PAST ISSUES ETOC COLLECTIONS
AUTHORS REVIEWERS EDITORIAL BOARD FEEDBACK RSS HELP
A&A International Anesthesia Research Society
QUICK SEARCH:   [advanced]


     

Anesth Analg 1983; 62:164-167
© 1983 International Anesthesia Research Society
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a colleague
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bullingham, R.
Right arrow Articles by Moore, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bullingham, R.
Right arrow Articles by Moore, A.

Perineural Injection of Morphine Fails to Relieve Postoperative Pain in Humans

Roy Bullingham, FFARCS, Geraldine O'Sullivan, FFARCS, Henry McQuay, FFARCS, Patsy Poppleton, SRN, Marney Rolfe, SRN, Peter Evans, FFARCS, and Andrew Moore, DPhil

Pain Relief Research Unit, Oxford Regional Pain Relief Unit, Abingdon Hospital, Abingdon, Oxon, England.

Abstract

Ten patients scheduled for bilateral foot surgery were given general anesthesia plus ankle blocks. One side was blocked with 0.02% morphine and the other with 0.9% saline. A second group of 10 patients for bilateral foot surgery had one side blocked with 0.02% morphine and the other with 0.01% morphine. A within-patient blind comparison of postoperative analgesia between the two sides was performed by nurse observers, using categorical and visual analogue scales for both pain intensity and pain relief. Postoperative analgesia recorded by the nurse observer was not significantly different between morphine and saline. Similarly, there was no significant difference in postoperative analgesia between legs blocked with the higher or lower dose of morphine. Thus, perineural morphine does not relieve postoperative pain at doses equivalent to 2–4 mg in a 70-kg man.

Key Words: ANALGESICS: morphine






Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1983 by the International Anesthesia Research Society.