JOURNAL HOME CME HOME THIS MONTH PAST ISSUES ETOC COLLECTIONS
AUTHORS REVIEWERS EDITORIAL BOARD FEEDBACK RSS HELP
A&A International Anesthesia Research Society
QUICK SEARCH:   [advanced]


     

Anesth Analg 1983; 62:181-185
© 1983 International Anesthesia Research Society
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a colleague
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Koller, M.-E.
Right arrow Articles by Breivik, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Koller, M.-E.
Right arrow Articles by Breivik, H.

Effects of Hypo-, Normo-, and Hypercarbia in Dogs with Acute Cardiac Tamponade

Mai-Elin Koller, MD, PhD, R. Brian Smith, MD, Ulf Sjöstrand, MD, PhD, and Harold Breivik, MD, PhD

Department of Anesthesiology, The University of Texas Health Science Center, San Antonio, Texas.

Abstract

The hemodynamic effects of changes in Paco2 during intermittent positive pressure ventilation (IPPV) were studied in nine dogs with acute cardiac tamponade. During steady state light thiopental anesthesia, measurements were performed during hypocarbia (24.0 ± 2.6), normocarbia (40.4 ± 2.4), and hypercarbia (56.8 ± 3.1 mm Hg; mean ± SD). The study was carried out at a standardized level of cardiac tamponade that gave a 60% reduction in cardiac output (CO) at normocarbia. Changes in airway pressure were avoided by adding CO2 to the inspiratory gas to obtain the desired Paco2. Hypercarbia increased pericardial pressure 2–4 mm Hg and significantly decreased CO. During hypocarbia CO increased as pericardial pressure decreased 3–6 mm Hg. These findings are the reverse of changes seen when tamponade is not present. The changes in pericardial pressure most likely influence myocardial tone and cardiac volume and, thus, CO. The results suggest that patients with cardiac tamponade requiring general anesthesia should not breathe spontaneously if there is any danger of respiratory depression and hypercarbia.

Key Words: HEART: cardiac tamponade • CARBON DIOXIDE: hypercarbia, hypocarbia






Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1983 by the International Anesthesia Research Society.