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Alcuronium and Intraocular Pressure

Received from the Departments of Anesthesia and Intensive Care Unit of the Theagenion Medical Institute and AHEPA Hospital, Thessaloniki, Greece.

Abstract

The effect of alcuronium on intraocular pressure (IOP) was studied in 20 patients undergoing elective ophthalmic surgery. IOP was measured with the Schiötz identation tonometer before induction, after induction, and after tracheal intubation. Combined administration of a standardized sleep dose of thiopental (5 mg/kg) and alcuronium (0.25—0.30 mg/kg) significantly (P < 0.001) decreased IOP from control values of 15.3 ± 2.33 mm Hg (mean ± SD) to 8.91 ± 2.15 mm Hg. Intubation of the trachea significantly (P < 0.001) increased IOP to 12.58 ± 3.05 mm Hg, a level still significantly (P < 0.001) lower than control values.

Key Words: NEUROMUSCULAR RELAXANTS: alcuronium • EYE: intraocular pressure

Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999