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Anesth Analg 1983; 62:578-580
© 1983 International Anesthesia Research Society
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Plasma Concentrations of Lidocaine Associated with Cervical, Thoracic, and Lumbar Epidural Anesthesia

Takahisa Mayumi, MD, Shuji Dohi, MD, and Takeo Takahashi, MD

Received from the Department of Anesthesia, Asahikawa City Hospital, 1 Chome Kinseicho, Asahikawa, Hokkaido, 070, Japan.

Abstract

We measured arterial plasma concentrations of lidocaine by enzyme immunoassay when 10 ml of 2% lidocaine without epinephrine was injected into the cervical, thoracic, or lumbar epidural spaces in 30 patients. There was no difference in the time courses of plasma levels of lidocaine. Peak concentrations were achieved 10 min after injection and were similar regardless of the site of injection. These results indicate the absence of significant differences in the rate of vascular absorption of lidocaine from different parts of the epidural space.

Key Words: ANESTHETIC TECHNIQUES: epidural • ANESTHETICS, Local: lidocaine




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Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1983 by the International Anesthesia Research Society.