JOURNAL HOME CME HOME THIS MONTH PAST ISSUES ETOC COLLECTIONS AUTHORS REVIEWERS EDITORIAL BOARD FEEDBACK RSS HELP
		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a colleague Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Ford, D. J. Articles by Raj, P. P. Search for Related Content PubMed PubMed Citation Articles by Ford, D. J. Articles by Raj, P. P.

Duration and Toxicity of Bupivacaine for Topical Anesthesia of the Airway in the Cat

Department of Anesthesia, University of Cincinnati College of Medicine, Cincinnati, Ohio.

Abstract

To assess bupivacaine as a topical anesthetic of the airway, 0.5 ml of 1, 2, and 4% bupivacaine was sprayed down the trachea of lightly anesthetized cats and the duration of anesthesia, systemic toxicity, and local toxicity was compared to that produced by 4% lidocaine. Two percent bupivacaine suppressed the cough reflex longer than 4% lidocaine with no increase in either local or systemic toxicity. Four percent bupivacaine produced arrhythmias in 5 of 10 cats in two groups and apnea in 4 of 6 cats. This study indicates that 2% would be an appropriate concentration to assess bupivacaine as a topical anesthetic of the airway in humans.

Key Words: ANESTHETICS, LOCAL—bupivacaine, lidocaine • ANESTHETIC TECHNIQUES—topical

Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999