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Anesth Analg 1984; 63:998-1000
© 1984 International Anesthesia Research Society
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Use of Cyclopropane to Test Generality of Anesthetic Requirement in the Elderly

Edwin S. Munson, MD, Joseph C. Hoffman, MD, and Edmond I. Eger, II, MD

Department of Anesthesiology, University of Florida College of Medicine and the Anesthesiology Service, Veterans Administration Medical Center, Gainesville, Florida, and from the Department of Anesthesia, University of California, San Francisco, California.

Abstract

The minimum alveolar concentration (MAC) of cyclopropane was determined in young (mean age, 32 yr; n = 16) and older (mean age, 81 yr; n = 12) surgical patients. Cyclopropane requirement was 23% lower in the elderly (P < 0.01). This reduction in anesthetic requirement with age is similar to that reported previously for halothane and isoflurane and supports the thesis of a general effect of age on anesthetic requirement.

Key Words: POTENCY, ANESTHETIC—age, cyclopropane • AGE FACTORS—anesthetic potency • ANESTHETICS, GASES—cyclopropane




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Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1984 by the International Anesthesia Research Society.