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Anesth Analg 1985; 64:996-1000
© 1985 International Anesthesia Research Society
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Comparison of the Effects of General and Regional Anesthesia for Cesarean Section on Neonatal Neurologic and Adaptive Capacity Scores

Therese K. Abboud, MD, Shakuntala Nagappala, MD, Kazushige Murakawa, MD, Saul David, MD, Sarkis Haroutunian, MD, Makrouhi Zakarian, MD, Thormason Yanagi, MD, and Amir Sheikh-Ol-Eslam, MD

Department of Anesthesiology, Los Angeles County-University of Southern California Medical Center, Los Angeles, California.

Abstract

Fifty-two neonates delivered by elective cesarean section were evaluated using the Neonatal Neurologic and Adaptive Capacity Scores. Twenty of the mothers received general anesthesia, 14 received epidural, and 18 received spinal anesthesia. All mothers receiving regional anesthesia were prehydrated with 1000 ml of lactated Ringer's solution and were given oxygen via a transparent face mask. All mothers undergoing general anesthesia received thiopental for induction flouted by N2O-O2 (4 L:4 L) and 0.5% enfliirane until delivery of the baby. All mothers were healthy, not in labor, and were scheduled for elective cesarean section. All neonates weighed 2500 g or more, had Apgar scores of 7 or more at 1 and 5 min, and had normal acid base and blood gas data. Neonates delivered with general anesthesia scored significantly lower on some of the test items for adaptive capacity, passive tone, active tone, primary reflexes, and total scores at both 15 min and 2 hr of age (P < 0.05) than those delivered with either epidural or spinal anesthesia. Neonates delivered with epidural anesthesia scored lower than those delivered with spinal anesthesia on supporting reaction and motor activity at 2 hr of age (P < 0.05). All neonates had high scores at 24 hr, at which time there were no significant differences between the three groups.

Key Words: ANESTHESIA, OBSTETRIC




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A. Rodgers, N. Walker, S Schug, A McKee, H Kehlet, A van Zundert, D Sage, M Futter, G Saville, T Clark, et al.
Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: results from overview of randomised trials
BMJ, December 16, 2000; 321(7275): 1493 - 1493.
[Abstract] [Full Text]


Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1985 by the International Anesthesia Research Society.