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Anesth Analg 1985; 64:343-347
© 1985 International Anesthesia Research Society
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Accumulation of Methane, Acetone, and Nitrogen in the Inspired Gas during Closed-Circuit Anesthesia

Shigeho Morita, MD, William Latta, MD, Kate Hambro, RN, and Michael T. Snider, MD, PhD

Department of Anesthesia, University of Tokyo Hospital, Tokyo, Japan; the Department of Anesthesia, Massachusetts General Hospital, Boston, Massachusetts; and the Department of Anesthesia, Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, Pennsylvania.

Abstract

During closed-circuit anesthesia, the patient's inspired gas may become progressively contaminated by nonanesthetic gases. We studied the concentrations of methane, acetone, and nitrogen as nonanesthetic gas contaminants in the circuit gas of 16 cases during closed-circuit anesthesia. After a "short" period of denitrogenation (6–8 min), average nitrogen concentration in the closed circuit increased from 6.4 to 16.2%, methane from 4.3 to 22.4 ppm, and acetone from 0.3 to 2.2 ppm. After "long" denitrogenation (33 min), average nitrogen concentration in the closed circuit increased from 1.0 to 5.1%, methane from 3.7 to 17.9 ppm, and acetone from 1.3 to 5.9 ppm. It is concluded that gases stored in tissues or produced within the body can appear in the patient's expired gas during closed-circuit anesthesia. Intermittent flushing of the circuit with high flow gases is suggested to remove these contaminants.

Key Words: ANESTHETIC TECHNIQUES—closed circuit • EQUIPMENT—circuits, closed




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Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1985 by the International Anesthesia Research Society.