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Anesthesia for Termination of Pregnancy

Midazolam Compared with Methohexital

The Department of Anesthesia, Queen's Medical Centre, University Hospital and Medical School, Nottingham, England.

Abstract

Clinical effects of intermittent intravenous administration of midazolam were compared with those of methohexital in two groups of ten premedicated patients each undergoing suction termination of pregnancy under general anesthesia. Both groups received intravenous fentanyl (1µg/kg) 5 min prior to administration of the induction agent. No significant difference was found between the two groups in induction time and quality of anesthesia. The recovery time was significantly (17 min) longer in patients who received midazolam (P < 0.0001).

Key Words: HYPNOTICS, BENZODIAZEPINES—Midazolam. • HYPNOTICS, BARBITUATES—methohexital. • ANESTHESIA, INTRAVENOUS—midazolam, methohexital.

Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999