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Anesth Analg 1986; 65:1004-1006
© 1986 International Anesthesia Research Society
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Effect of Etomidate on the Electroencephalogram of Patients with Epilepsy

Zeyd Y. Ebrahim, MD, Glenn E. DeBoer, MD, Hans Luders, MD, Joseph F. Hahn, MD, and Ronald P. Lesser, MD

Division of Anesthesiology, Department of Neurology, and the Department of Neurosurgery, The Cleveland Clinic Foundation, Cleveland, Ohio.

Abstract

Etomidate was given intravenously to 12 epileptic patients undergoing craniotomy for surgical removal of their seizure focus. Electroencephalograms were recorded by means of subdural electrodes. Nine of the 12 patients showed an increase in epileptiform activity. In six of the nine patients, the activity was marked.

Key Words: ANESTHETICS, INTRAVENOUS—etomidate • COMPLICATIONS—epilepsy




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Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1986 by the International Anesthesia Research Society.