| JOURNAL HOME | CME HOME | THIS MONTH | PAST ISSUES | ETOC | COLLECTIONS |
| AUTHORS | REVIEWERS | EDITORIAL BOARD | FEEDBACK | RSS | HELP |
| ||||||||||||||
| ||||||||||||||
|
|
|
|
||||||||||||
|
||||||||||||||
Departments of Anaesthesia and Medicine, Foothills Hospital at the University of Calgary, Calgary, Alberta, Canada.
Abstract
The effects of preoperative oral administration of 150 ml fluid were studied prospectively in 140 unpremedicated, ambulateray outpatients presenting for first trimester therapeutic abortion. Intraoperative gastric fluid volume, pH, and rate of gastric emptying were measured in the four groups to which patients were randomly assigned. At an average of 2 1/2 hr preoperatively all patients received either oral ranitidine, 15 mg, or a placebo tablet, with the nonabsorbable marker dye bromosuluphthalein (BSP), 50 mg in 10 ml water, followed by either 150 ml water or no further fluid. The effect of volume ingested was assessed by comparing the volume of gastric contents obtained by gastric tube suctioning at the completion of surgery in the two groups given placebos. The gastric volume was significantly less in patients given 15 ml water (17.6 ± 14.5) than in those given only BSP (26.7 ± 18.9) (P < 0.02), and was the further significantly decreased in the two groups given ranitidine (8.3 ± 7.3, 9.5 ± 7.7 ml) (P < 0.001). Mean pH values were significantly higher in the two ranitidine groups (5.52 ± 1.79, 5.03 ± 1.79) than in the two placebo groups (1.75 ± 0.94, 1.92 ± 1.27). The combination of a residual volume of 25 ml and pH less than 2.5 was found in 46% of patients given only BSP with placebo, in 23% of those given 150ml water with placebo and in no patient given ranitidine. There was no correlation between the gastric volume or pH values with the ingestion-surgery interval in patients given 150 ml water.
Key Words: GASTROINTESTINAL TRACT—gastric emptying • HISTAMINE—ranitidine • ANESTHESIA—outpatient
This article has been cited by other articles:
|
|
 |
|
  C. A. Wong, R. J. McCarthy, P. C. Fitzgerald, K. Raikoff, and M. J. Avram Gastric Emptying of Water in Obese Pregnant Women at Term Anesth. Analg., September 1, 2007; 105(3): 751 - 755. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. M. Davies Changing anesthetic practice: walking to the OR/Evolution de la pratique de l'anesthesie : marcher vers la salle d'operation Can J Anesth, October 1, 2002; 49(8): 772 - 776. [Full Text] [PDF]
|
|
|
|
|
|
S. G. Lindahl Not Only Towards Enhanced Preoperative Comfort Anesth. Analg., November 1, 2001; 93(5): 1091 - 1092. [Full Text] [PDF]
|
|
|
|
|
|
J. Hausel, J. Nygren, M. Lagerkranser, P. M. Hellstrom, F. Hammarqvist, C. Almstrom, A. Lindh, A. Thorell, and O. Ljungqvist A Carbohydrate-Rich Drink Reduces Preoperative Discomfort in Elective Surgery Patients Anesth. Analg., November 1, 2001; 93(5): 1344 - 1350. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Naguib, A. H. Samarkandimb, Y. Al-Hattab, A. Turkistani, M. B. Delvi, W. Riad, and M. Attia Metabolic, hormonal and gastric fluid and pH changes after different preoperative feeding regimens Can J Anesth, April 1, 2001; 48(4): 344 - 350. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. K. Pandit, K. W. Loberg, and U. A. Pandit Toast and Tea Before Elective Surgery? A National Survey on Current Practice Anesth. Analg., June 1, 2000; 90(6): 1348 - 1351. [Abstract] [Full Text] [PDF]
|
|
|
