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Effects of Alfentanil and Fentanyl on Common Bile Duct Pressure

Received from the Department of Anaesthesia and the Second Department of Surgery, Helsinki University Central Hospital, Helsinki, Finland.

Abstract

The effects of alfentanil (7.5 or 15 µg/kg) and fentanyl (1.5 µg/kg) on common bile duct pressure were examined by using an indwelling postoperative T-tube in 36 conscious, unpremedicated patients. All opiate doses significantly (P < 0.001) increased the pressure. There was no significant difference among the groups in the peak pressures nor in the times to peak pressures. Fentanyl had a significantly longer duration of effect on pressure.

Key Words: ANALGESICS—alfentanil • LIVER—biliary tract pressure

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Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999