JOURNAL HOME CME HOME THIS MONTH PAST ISSUES ETOC COLLECTIONS
AUTHORS REVIEWERS EDITORIAL BOARD FEEDBACK RSS HELP
A&A International Anesthesia Research Society
QUICK SEARCH:   [advanced]


     

Anesth Analg 1989; 68:201-207
© 1989 International Anesthesia Research Society
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a colleague
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by de Bruijn, N. P.
Right arrow Articles by Stack, R. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by de Bruijn, N. P.
Right arrow Articles by Stack, R. S.

General Anesthesia During Percutaneous Transluminary Coronary Angioplasty for Acute Myocardial Infarction

Results of a Randomized Controlled Clinical Trial

Norbert P. de Bruijn, MD, Mark A. Hlatky, MD, James R. Jacobs, PhD, Fiona M. Clements, MD, Narda D. Croughwell, CRNA, Deborah Davis, CRNA, Paolo Flezzani, MD, Russell F. Hill, MD, Tomoaki Hinohara, MD, Robert A. Kates, MD, Joannes H. Karis, MD, William McIntyre, MD, J. G. Reves, MD, and Richard S. Stack, MD

Division of Cardiovascular-Thoracic Anesthesia, Department of Anesthesiology, and the Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina.

Abstract

Acutely ill patients with myocardial infarction may require immediate cardiac catheterization and coronary angioplasty to achieve myocardial reperfusion. To determine the feasibility of using general anesthesia under these circumstances, a randomized clinical trial was performed. Of 50 patients, 25 received anesthesia and 25 received intravenous sedation. There were transient increases in heart rate and blood pressure after tracheal intubation in the anesthetized patients, followed by significant and sustained decreases below baseline values once steady state anesthesia was attained. Arterial oxygenation was significantly improved in anesthetized patients. There were no serious complications due to anesthesia, but the small sample size limited the power of the study to detect differences in morbidity or mortality. Patients strongly preferred anesthesia. These results show that general anesthesia is feasible in patients undergoing interventional cardiac catheterization during acute myocardial infarction,. when pain, anxiety or agitation do not respond adequately to conventional measures.

Key Words: ANESTHESIA, cardiovascular • HEART, MYOCARDIAL INFARCTION—angioplasty
Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins and Stanford University Libraries' HighWire Press®. Copyright 1989 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1989 by the International Anesthesia Research Society.