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Anesthetic Management of a Pregnant Patient With the Hyperimmunoglobulin E (Job's) Syndrome

Center for Research in Anesthesia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.

Abstract

The hyperimmunoglobulin E (HIE) syndrome, also known as Job's syndrome, is a rare disorder associated with recurrent bacterial infections and abscesses of the skin and respiratory tract, primarily due to Staphylococcus aureus, and high serum immunoglobulin E (IgE) levels (1,2). The disorder begins in early childhood. There is no effective treatment, and these patients must present repeatedly for surgical drainage of abscesses. This case report describes the anesthetic management of a pregnant patient with HIE who presented for drainage of a hip abscess.

Key Words: GENETIC FACTORS, JOB'S SYNDROME. • ANESTHETIC TECHNIQUES, EPIDURAL—immunologic deficiency. • IMMUNE RESPONSE, DEFICIENCY—epidural anesthesia.