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Anesth Analg 1990; 71:191-193
© 1990 International Anesthesia Research Society
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Delayed Recognition of Podophyllum Toxicity in a Patient Receiving Epidural Morphine

Pattilynn F. Conard, CRNA, BA, Nivine Hanna, MD, Martin Rosenblum, PhD, MD, and Jeffrey B. Gross, MD

Department of Anesthesiology, University of Connecticut School of Medicine, Farmington, Connecticut.

Abstract

Podophyllum is frequently used by both dermatologists and gynecologists for the treatment of condylomata acuminata. However, the potential toxicity of topically applied podophyllum is not widely appreciated. We describe below a postanesthetic death directly related to topically applied podophyllum; diagnosis and treatment may have been delayed because early symptoms of podophyllum toxicity were incorrectly attributed to epidural morphine, which we had administered for postoperative pain control.

Key Words: TOXICITY, PODOPHYLLUM • ANESTHETIC TECHNIQUES, EPIDURAL-morphine.
Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins and Stanford University Libraries' HighWire Press®. Copyright 1990 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 1990 by the International Anesthesia Research Society.