Anesthesia & Analgesia, Vol 80, 682-686, Copyright © 1995 by International Anesthesia Research Society

GENERAL ARTICLES

A prospective randomized double-blinded study of the effect of intravenous fluid therapy on adverse outcomes on outpatient surgery

S Yogendran, B Asokumar, DC Cheng and F Chung
Department of Anaesthesia, University of Toronto, Ontario, Canada.

This study investigated the impact of perioperative fluid status on adverse clinical outcomes in ambulatory surgery. Two hundred ASA grade I-III ambulatory surgical patients were prospectively randomized into two groups to receive high (20 mL/kg) or low (2 mL/kg) infusions of isotonic electrolyte solution over 30 min preoperatively. A standardized balanced anesthetic was used. A minimal amount of fluid was given during the intraoperative and postoperative periods. Adverse outcomes were assessed by an investigator blinded to the fluid treatment group at 30 and 60 min after surgery, at discharge, and the first postoperative day. The incidence of thirst, drowsiness, and dizziness was significantly lower in the high-infusion group at all intervals. We recommend perioperative hydration of 20 mL/kg for patients undergoing general anesthesia for short ambulatory surgery.

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