This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a colleague Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Web of Science (8) Citing Articles via Google Scholar Google Scholar Articles by Frankowski, G. A. Articles by Tobias, J. D. Search for Related Content PubMed PubMed Citation Articles by Frankowski, G. A. Articles by Tobias, J. D.

---

PEDIATRIC ANESTHESIA

Rapacuronium Administration to Two Children with Duchenne’s Muscular Dystrophy

Gary A. Frankowski, MD^*, Joel O. Johnson, MD, PhD^*,, and Joseph D. Tobias, MD^*,,§

Departments of *Anesthesiology, Neurosurgery, and Pediatrics and §Division of Pediatric Critical Care/Pediatric Anesthesiology, The University of Missouri, Columbia, Missouri

Address correspondence and reprint requests to Joseph D. Tobias, MD, Professor of Anesthesiology and Child Health,The University of Missouri, Department of Child Health, M658 Health Sciences Center, One Hospital Dr., Columbia, MO 65212. Address e-mail to Tobiasj{at}health.missouri.edu

Implications: Children with Duchenne’s muscular dystrophy should not be exposed to succinylcholine because of the risk of hyperkalemic cardiac arrest and rhabdomyolysis. This report describes the response to rapacuronium bromide in two patients with Duchenne’s muscular dystrophy. Both patients had a recovery index 2 times longer than that reported in children with normal neuromuscular function.

This article has been cited by other articles:

				J. Schmidt, T. Muenster, S. Wick, J. Forst, and H. J. Schmitt Onset and duration of mivacurium-induced neuromuscular block in patients with Duchenne muscular dystrophy Br. J. Anaesth., December 1, 2005; 95(6): 769 - 772. [Abstract] [Full Text] [PDF]