This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a colleague Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Web of Science (23) Citing Articles via Google Scholar Google Scholar Articles by O’Connor, C. J. Articles by Tuman, K. J. Search for Related Content PubMed PubMed Citation Articles by O’Connor, C. J. Articles by Tuman, K. J.

---

CARDIOVASCULAR ANESTHESIA

Pulmonary Thromboembolism During Liver Transplantation: Possible Association with Antifibrinolytic Drugs and Novel Treatment Options

Christopher J. O’Connor, MD^*, David Roozeboom, CRNA, Russell Brown, CCP, and Kenneth J. Tuman, MD^*

*Department of Anesthesiology, School of Nursing, and School of Perfusion Technology, Rush Medical College, Rush-Presbyterian-St. Lukes Medical Center, Chicago, Illinois

Address correspondence and reprint requests to Christopher J. O’Connor, MD, Department of Anesthesiology, Rush-Presbyterian-St. Lukes Medical Center, 1653 W. Congress Pkwy., Chicago, IL 60612. Address e-mail to coconnor{at}rpslmc.edu

Implications: The authors describe two cases of massive intraoperative pulmonary thromboembolism resulting in cardiovascular collapse during liver transplantation. The potential role of antifibrinolytic drugs is discussed, along with the use of treatment modalities not previously applied in this setting.

This article has been cited by other articles:

				F. Mahmood, A. Christie, and R. Matyal Transesophageal Echocardiography and Noncardiac Surgery Seminars in Cardiothoracic and Vascular Anesthesia, December 1, 2008; 12(4): 265 - 289. [Abstract] [PDF]

				D. Jackson, A. Botea, Y. Gubenko, E. Delphin, and H. Bennett Successful intraoperative use of recombinant tissue plasminogen activator during liver transplantation complicated by massive intracardiac/pulmonary thrombosis. Anesth. Analg., March 1, 2006; 102(3): 724 - 728. [Abstract] [Full Text] [PDF]

				A. B. Lerner, E. Sundar, F. Mahmood, T. Sarge, D. W. Hanto, and P. J. Panzica Four Cases of Cardiopulmonary Thromboembolism During Liver Transplantation Without the Use of Antifibrinolytic Drugs Anesth. Analg., December 1, 2005; 101(6): 1608 - 1612. [Abstract] [Full Text] [PDF]

				C. Lentschener, K. Roche, and Y. Ozier A Review of Aprotinin in Orthotopic Liver Transplantation: Can Its Harmful Effects Offset Its Beneficial Effects? Anesth. Analg., May 1, 2005; 100(5): 1248 - 1255. [Abstract] [Full Text] [PDF]

				R. M. Planinsic, R. Nicolau-Raducu, B. Eghtesad, and A. Marcos Diagnosis and Treatment of Intracardiac Thrombosis During Orthotopic Liver Transplantation Anesth. Analg., August 1, 2004; 99(2): 353 - 356. [Abstract] [Full Text] [PDF]

				L. Massicotte, M.-P. Sassine, S. Lenis, and A. Roy Transfusion Predictors in Liver Transplant Anesth. Analg., May 1, 2004; 98(5): 1245 - 1251. [Abstract] [Full Text] [PDF]

				I. Q. Molenaar, R. J. Porte, M. G. Fitzsimons, and R. A. Peterfreund Aprotinin and Thromboembolism in Liver Transplantation: Is There Really a Causal Effect? * Response Anesth. Analg., May 1, 2002; 94(5): 1367 - 1368. [Full Text] [PDF]

				M. G. Fitzsimons, R. A. Peterfreund, and D. E. Raines Aprotinin Administration and Pulmonary Thromboembolism During Orthotopic Liver Transplantation: Report of Two Cases Anesth. Analg., June 1, 2001; 92(6): 1418 - 1421. [Full Text] [PDF]

				B. M. Parker, S. A. Irefin, C. J. O'Connor, and K. J. Tuman Antifibrinolytic Therapy and Pulmonary Thromboembolism During Orthotopic Liver Transplantation Anesth. Analg., February 1, 2001; 92(2): 559 - 560. [Full Text] [PDF]