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CARDIOVASCULAR ANESTHESIA

Pulmonary Thromboembolism During Liver Transplantation: Possible Association with Antifibrinolytic Drugs and Novel Treatment Options

Christopher J. O’Connor, MD^*, David Roozeboom, CRNA, Russell Brown, CCP, and Kenneth J. Tuman, MD^*

*Department of Anesthesiology, School of Nursing, and School of Perfusion Technology, Rush Medical College, Rush-Presbyterian-St. Lukes Medical Center, Chicago, Illinois

Address correspondence and reprint requests to Christopher J. O’Connor, MD, Department of Anesthesiology, Rush-Presbyterian-St. Lukes Medical Center, 1653 W. Congress Pkwy., Chicago, IL 60612. Address e-mail to coconnor{at}rpslmc.edu

Implications: The authors describe two cases of massive intraoperative pulmonary thromboembolism resulting in cardiovascular collapse during liver transplantation. The potential role of antifibrinolytic drugs is discussed, along with the use of treatment modalities not previously applied in this setting.

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Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999