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REGIONAL ANESTHESIA AND PAIN MEDICINE

Downbeat Nystagmus Associated with Intravenous Patient-Controlled Administration of Morphine

Department of Neurology, Mayo Clinic, Rochester, Minnesota

Address correspondence and reprint requests to E. F. M. Wijdicks, MD, Mayo Clinic, Department of Neurology, 200 First St. SW, Rochester, MN 55905. Address e-mail to wijde{at}mayo.edu

Implications: This case documents a patient who developed dizziness with downbeating nystagmus while receiving a relatively large dose of IV patient-controlled analgesia morphine. Although there have been case reports of epidural morphine with these symptoms and signs, this has not been previously documented with IV or patient-controlled analgesia morphine.