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The Effect of Sedative Drugs on Diaphragmatic Contractility in Dogs: Propofol Versus Midazolam

Department of Anesthesiology, University of Tsukuba Institute of Clinical Medicine, Tsukuba City, Ibaraki, Japan

Address correspondence and reprint requests to Yoshitaka Fujii, Department of Anesthesiology, University of Tsukuba Institute of Clinical Medicine, 2-1-1, Amakubo, Tsukuba City, Ibaraki 305, Japan.

Implications: A sedative dose (0.1 mg · kg^-1 · h^-1) of midazolam, compared with a subhypnotic dose (1.5 mg · kg^-1 · h^-1) of propofol, decreases the contractility of the diaphragm in dogs.

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