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Anesth Analg 2001;92:249-251
© 2001 International Anesthesia Research Society

REGIONAL ANESTHESIA AND PAIN MEDICINE

Diffuse Brachial Plexopathy After Interscalene Blockade in a Patient Receiving Cisplatin Chemotherapy: The Pharmacologic Double Crush Syndrome

James R. Hebl, MD, Terese T. Horlocker, MD, and Douglas J. Pritchard, MD**

Departments of Anesthesiology and *Orthopedic Surgery, Mayo Clinic and Foundation, Rochester, Minnesota

Address correspondence to James R. Hebl, MD, Department of Anesthesiology, Mayo Clinic, 200 First Street, S.W., Rochester, MN 55905. Address e-mail to hebl.james{at}mayo.edu

Implications: Sensory peripheral neuropathy is a common toxic side effect in patients undergoing cisplatin chemotherapy. The peripheral nerve fibers of these patients may therefore be more susceptible to the toxic effects of local anesthetics. As a result, regional anesthetic techniques should be used with caution within this patient population to avoid potentially devastating and irreversible neurologic sequelae.






Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins and Stanford University Libraries' HighWire Press®. Copyright 2001 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2001 by the International Anesthesia Research Society.