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Anesth Analg 2001;92:415-417
© 2001 International Anesthesia Research Society

NEUROSURGICAL ANESTHESIA

The Effect of Continuous Positive Airway Pressure on Cerebral Blood Flow Velocity in Awake Volunteers

Robert A. Bowie, FRCA, Paddy J. O’Connor, FRCA, Jonathan G. Hardman, FRCA, and Ravi P. Mahajan, FFARCSI

University Department of Anaesthesia and Intensive Care, City Hospital, Nottingham, UK

Address correspondence and reprint requests to Dr. Ravi P. Mahajan, Department of Anaesthesia, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB. Address e-mail to ravi.mahajan{at}nottingham.ac.uk

We measured the effect of 5 and 10 cm H2O continuous positive airways pressure (CPAP) on middle cerebral artery blood flow velocity (FV) in 15 awake, healthy volunteers by using transcranial Doppler ultrasonography. Mean, systolic, and diastolic FV plus pulsatility index were recorded. No significant change in any measured variable was observed with the application of 5 or 10 cm H2O CPAP. These results are in contrast to those of a previous study, which found a significant increase in mean FV and a decrease in pulsatility index during the application of 12 cm H2O CPAP.

Implications: Our study implies that the application of continuous positive airway pressure (CPAP) does not affect transcranial Doppler monitoring of the middle cerebral artery blood flow velocity and that the effect of CPAP on cerebral hemodynamics is less than had been previously suggested.






Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2001 by the International Anesthesia Research Society.