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Anesth Analg 2001;92:625-628
© 2001 International Anesthesia Research Society


AMBULATORY ANESTHESIA

Intraarticular Sufentanil Administration Facilitates Recovery After Day-Case Knee Arthroscopy

Jan H. Vranken, MD, Kris C. P. Vissers, MD*, Raf de Jongh, MD*, and Rene Heylen, MD, PhD*

Department of Anesthesiology, Academic Medical Center, University of Amsterdam, 1100 DD Amsterdam, The Netherlands; and *Department of Anesthesiology, Ziekenhuis Oost-Limburg, 3600 Genk, Belgium

Address correspondence and reprint requests to Jan H. Vranken, MD, Department of Anesthesiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. Address e-mail to jannekevranken{at}hotmail.com

We evaluated the efficacy of intraarticular sufentanil in the prevention of postoperative pain after day-case arthroscopic procedures. Sixty patients were randomly assigned to receive either intraarticular sufentanil, 5 or 10 µg, and saline IV, or intraarticular saline and sufentanil 5 µg IV (control). All study medication was administered in a double-blinded fashion. Postoperatively and the day after surgery, pain levels at rest and during movement (i.e., active flexion of the knee), measured by a visual analog scale, were significantly lower in the Sufentanil groups compared with the Control group. Moreover, intraarticular sufentanil significantly reduced the postoperative consumption of analgesics. The time until discharge from the postanesthesia care unit (assessed by the Aldrete score) was significantly shorter in the patients receiving sufentanil intraarticularly. There were no significant differences between the two Sufentanil groups either in the intensity of postoperative pain or in discharge times from the postanesthesia care unit. We conclude that intraarticular sufentanil in arthroscopic knee procedures is a simple, effective, safe and well-tolerated analgesic technique for outpatients undergoing arthroscopic procedures. Increasing the dose sufentanil from 5 to 10 µg intraarticularly offered no additional advantage. Intraarticular sufentanil (5–10 µg) administration improves postoperative management after day-case diagnostic arthroscopic knee procedures.

Implications: Intraarticular sufentanil (5–10 µg) administration improves postoperative management after day-case diagnostic arthroscopic knee procedures.




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M. Kizilkaya, O. S. Yildirim, N. Dogan, H. Kursad, and A. Okur
Analgesic Effects of Intraarticular Sufentanil and Sufentanil Plus Methylprednisolone After Arthroscopic Knee Surgery
Anesth. Analg., April 1, 2004; 98(4): 1062 - 1065.
[Abstract] [Full Text] [PDF]




Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2001 by the International Anesthesia Research Society.