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Department of Anesthesiology, Academic Medical Center, University of Amsterdam, 1100 DD Amsterdam, The Netherlands; and *Department of Anesthesiology, Ziekenhuis Oost-Limburg, 3600 Genk, Belgium
Address correspondence and reprint requests to Jan H. Vranken, MD, Department of Anesthesiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. Address e-mail to jannekevranken{at}hotmail.com
We evaluated the efficacy of intraarticular sufentanil in the prevention of postoperative pain after day-case arthroscopic procedures. Sixty patients were randomly assigned to receive either intraarticular sufentanil, 5 or 10 µg, and saline IV, or intraarticular saline and sufentanil 5 µg IV (control). All study medication was administered in a double-blinded fashion. Postoperatively and the day after surgery, pain levels at rest and during movement (i.e., active flexion of the knee), measured by a visual analog scale, were significantly lower in the Sufentanil groups compared with the Control group. Moreover, intraarticular sufentanil significantly reduced the postoperative consumption of analgesics. The time until discharge from the postanesthesia care unit (assessed by the Aldrete score) was significantly shorter in the patients receiving sufentanil intraarticularly. There were no significant differences between the two Sufentanil groups either in the intensity of postoperative pain or in discharge times from the postanesthesia care unit. We conclude that intraarticular sufentanil in arthroscopic knee procedures is a simple, effective, safe and well-tolerated analgesic technique for outpatients undergoing arthroscopic procedures. Increasing the dose sufentanil from 5 to 10 µg intraarticularly offered no additional advantage. Intraarticular sufentanil (510 µg) administration improves postoperative management after day-case diagnostic arthroscopic knee procedures.
Implications: Intraarticular sufentanil (510 µg) administration improves postoperative management after day-case diagnostic arthroscopic knee procedures.
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