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Department of Anesthesia and Intensive Care, University of Rome "La Sapienza", Rome, Italy
Address correspondence and reprint requests to Federico Bilotta, MD, PhD, via dei Tadolini 13, Rome, 00196, Italy. Address e-mail to bilotta{at}tiscalinet.it
Refractory postoperative hiccups is an uncommon but distressing condition that might cause deleterious effects such as wound dehiscence, infection, fatigue, and dehydration. Our experience suggests that when standard therapeutic maneuvers fail, IV nefopam will promptly and reliably relieve refractory postoperative hiccups without inducing severe adverse reactions.
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