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Anesth Analg 2001;93:1557-1559
© 2001 International Anesthesia Research Society

NEUROSURGICAL ANESTHESIA

Paraneoplastic Syndromes Associated with Lung Cancer: A Unique Case of Concomitant Subacute Cerebellar Degeneration and Lambert-Eaton Myasthenic Syndrome

Brian M. Leonovicz, MD, Eric A. Gordon, MD PhD, and C. Thomas Wass, MD

Department of Anesthesiology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota

Address correspondence and reprint requests to C. Thomas Wass, MD, Department of Anesthesiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905. Address e-mail to wass.thomas{at}mayo.edu

IMPLICATIONS: We report an unusual case in which a patient with paraneoplastic subacute cerebellar degeneration (a brain disorder resulting from antibody production by a tumor located outside the skull) developed Lambert-Eaton Myasthenic Syndrome (antibody-mediated skeletal muscle weakness) that was not apparent until she underwent surgery. Failure to recognize this disease process can cause life-threatening respiratory distress.






Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins and Stanford University Libraries' HighWire Press®. Copyright 2001 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2001 by the International Anesthesia Research Society.