JOURNAL HOME CME HOME THIS MONTH PAST ISSUES ETOC COLLECTIONS
AUTHORS REVIEWERS EDITORIAL BOARD FEEDBACK RSS HELP
A&A International Anesthesia Research Society
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a colleague
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (26)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Cohen, I. T.
Right arrow Articles by Patel, K. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Cohen, I. T.
Right arrow Articles by Patel, K. M.
Anesth Analg 2002;94:1178-1181
© 2002 International Anesthesia Research Society

PEDIATRIC ANESTHESIA

The Effect of Fentanyl on the Emergence Characteristics After Desflurane or Sevoflurane Anesthesia in Children

Ira Todd Cohen, MD, Julia C. Finkel, MD, Raafat S. Hannallah, MD, Kelly A. Hummer, RN, and Kantilal M. Patel, PhD

Departments of Anesthesiology and Pediatrics, Children’s National Medical Center and George Washington University Medical Center, Washington, DC

Address correspondence and reprint requests to Ira Todd Cohen, MD, Department of Anesthesiology, Children’s National Medical Center, 111 Michigan Ave., NW, Washington, DC 20010. Address e-mail to icohen{at}cnmc.org

Desflurane and sevoflurane anesthesia are associated with emergence agitation in children. In this study, we examined the effect of a single intraoperative dose of fentanyl on emergence characteristics in children undergoing adenoidectomy. One hundred children, 2–7 yr old, were randomly assigned to receive desflurane or sevoflurane for maintenance of general anesthesia after an inhaled induction with sevoflurane and a 2.5 µg/kg dose of fentanyl. An observer blind-ed to the anesthetic technique assessed the times to achieve emergence, extubation and recovery criteria, as well as emergence behaviors. The results showed a similar incidence of severe emergence agitation after general anesthesia with desflurane (24%) and sevoflurane (18%). Times to achieve extubation and postanesthesia care unit discharge criteria were shorter with desflurane than with sevoflurane. With this technique, desflurane allows for a more rapid emergence and recovery than sevoflurane. In children receiving desflurane or sevoflurane, the concurrent use of fentanyl in a dose of 2.5 µg/kg results in a small incidence of emergence agitation.

IMPLICATIONS: The concurrent use of fentanyl in a dose of 2.5 µg/kg in children receiving desflurane or sevoflurane results in a low incidence of emergence agitation. Desflurane allows for a more rapid emergence and recovery than sevoflurane.




This article has been cited by other articles:


Home page
 Anesth. Analg.Home page
G. P. Vlajkovic and R. P. Sindjelic
Emergence Delirium in Children: Many Questions, Few Answers
Anesth. Analg., January 1, 2007; 104(1): 84 - 91.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
G. R. Nordmann, J. A. Read, S. M. Sale, P. A. Stoddart, and A. R. Wolf
Emergence and recovery in children after desflurane and isoflurane anaesthesia: effect of anaesthetic duration
Br. J. Anaesth., June 1, 2006; 96(6): 779 - 785.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
U. Lankinen, R. Avela, and P. Tarkkila
The prevention of emergence agitation with tropisetron or clonidine after sevoflurane anesthesia in small children undergoing adenoidectomy.
Anesth. Analg., May 1, 2006; 102(5): 1383 - 1386.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
J. Mayer, J. Boldt, K. D. Rohm, K. Scheuermann, and S. W. Suttner
Desflurane Anesthesia After Sevoflurane Inhaled Induction Reduces Severity of Emergence Agitation in Children Undergoing Minor Ear-Nose-Throat Surgery Compared with Sevoflurane Induction and Maintenance
Anesth. Analg., February 1, 2006; 102(2): 400 - 404.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
S. Tesoro, D. Mezzetti, L. Marchesini, and V. A. Peduto
Clonidine Treatment for Agitation in Children After Sevoflurane Anesthesia
Anesth. Analg., December 1, 2005; 101(6): 1619 - 1622.
[Abstract] [Full Text] [PDF]

Home page
 Am J Health Syst PharmHome page
A. Macario, F. Dexter, and D. Lubarsky
Meta-analysis of trials comparing postoperative recovery after anesthesia with sevoflurane or desflurane
Am. J. Health Syst. Pharm., January 1, 2005; 62(1): 63 - 68.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
T. Voepel-Lewis, S. Malviya, and A. R. Tait
A Prospective Cohort Study of Emergence Agitation in the Pediatric Postanesthesia Care Unit
Anesth. Analg., June 1, 2003; 96(6): 1625 - 1630.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
R. D. Valley, E. B. Freid, A. G. Bailey, V. J. Kopp, L. S. Georges, J. Fletcher, and A. Keifer
Tracheal Extubation of Deeply Anesthetized Pediatric Patients: A Comparison of Desflurane and Sevoflurane
Anesth. Analg., May 1, 2003; 96(5): 1320 - 1324.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
H. R. Munoz, M. E. Ibacache, and I. T. Cohen
Agitation After Desflurane and Dixon and Massey Up-and-Down Method * Response
Anesth. Analg., February 1, 2003; 96(2): 628 - 628.
[Full Text] [PDF]


Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2002 by the International Anesthesia Research Society.