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CARDIOVASCULAR ANESTHESIA

Intravascular Volume Replacement Therapy with Synthetic Colloids: Is There an Influence on Renal Function?

Joachim Boldt, MD^*, and Hans-Joachim Priebe, FRCA

*Department of Anesthesiology and Intensive Care Medicine, Klinikum der Stadt Ludwigshafen, Ludwigshafen, Germany; and Department of Anesthesia, University Hospital, Freiburg, Germany

Address correspondence and reprint requests to Prof. Dr. Joachim Boldt, Department of Anesthesiology and Intensive Care Medicine, Klinikum der Stadt Ludwigshafen, Bremserstr. 79, D-67063 Ludwigshafen, Germany. Address e-mail to BoldtJ{at}gmx.net

IMPLICATIONS: Articles on volume replacement published between 1981 and 2001 were analyzed. Albumin and gelatin do not predispose to development of kidney dysfunction. Modern hydroxyethyl starch (HES) solutions can be used safely in patients without kidney dysfunction even in large doses. Safety of HES in patients with preexisting altered kidney function still remains unclear.

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Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins with the assistance of Stanford University Libraries' HighWire Press®. Copyright 2006 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999