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Anesth Analg 2003;96:1096-1103
© 2003 International Anesthesia Research Society

PAIN MEDICINE

The Role of Interleukin-6 in Nociception and Pain

Raf F. De Jongh, MD*, Kris C. Vissers, MD*, Theo F. Meert, PhD{dagger}, Leo H. D. J. Booij, MD PhD, FRCA{ddagger}, Catharina S. De Deyne, MD PhD*, and René J. Heylen, MD PhD*

*Department of Anesthesia, Intensive Care, and Emergency Care and the Multidisciplinary Pain Centre, Ziekenhuis Oost Limburg, Genk, Belgium; {dagger}Johnson & Johnson, Pharmaceutical Research and Development, Beerse, Belgium; and {ddagger}Department of Anesthesia, University Hospital of Nijmegen, Nijmegen, The Netherlands

Address correspondence and reprint requests to R. De Jongh, MD, Department of Anesthesia, ZOL, Schiepse Bos 6, B 3600 Genk, Belgium. Address e-mail to raf.dejongh{at}zol.be

IMPLICATIONS: That IL-6 is an interesting target in the study of pain is underscored by its biomolecular properties, its localization after experimental pain, and its modulating effect on pain after administration.




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Lippincott, Williams & Wilkins Anesthesia & Analgesia® is published for the International Anesthesia Research Society® by Lippincott Williams & Wilkins and Stanford University Libraries' HighWire Press®. Copyright 2003 by the International Anesthesia Research Society. Online ISSN: 1526-7598   Print ISSN: 0003-2999 HighWire Press
Copyright © 2003 by the International Anesthesia Research Society.